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Related Experiment Video

Updated: Jul 17, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Potential and latent coeliac disease.

G K Holmes¹

¹Derbyshire Royal Infirmary, London Road, Derby DE1 1QY, UK.

European Journal of Gastroenterology & Hepatology

|September 21, 2001

Summary

Treating giardiasis in a child with coeliac disease resolved symptoms and normalized intestinal morphology. This suggests infection treatment can shift active coeliac disease to a latent form.

Area of Science:

Gastroenterology
Pediatric Medicine
Immunology

Background:

Coeliac disease is an autoimmune disorder triggered by gluten ingestion.
Potential and latent forms of coeliac disease are increasingly recognized.
Giardiasis is a common intestinal parasitic infection.

Observation:

A child presented with symptoms of both coeliac disease and giardiasis.
The patient received treatment solely for giardiasis, without a gluten-free diet.
Diarrhea symptoms resolved, and small intestinal morphology returned to normal post-treatment.

Findings:

Resolution of giardiasis infection led to a clinical and morphological remission of coeliac disease.
The patient transitioned from active to a latent form of coeliac disease.

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This indicates that parasitic infections can influence the presentation and activity of coeliac disease.

Implications:

Highlights the potential role of infections in modulating coeliac disease activity.
Suggests a paradigm shift in managing coeliac disease in the presence of concurrent infections.
Emphasizes the importance of considering latent coeliac disease and its clinical implications.