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Potential and latent coeliac disease.
1Derbyshire Royal Infirmary, London Road, Derby DE1 1QY, UK.
European Journal of Gastroenterology & Hepatology
|September 21, 2001
Summary
Treating giardiasis in a child with coeliac disease resolved symptoms and normalized intestinal morphology. This suggests infection treatment can shift active coeliac disease to a latent form.
Area of Science:
- Gastroenterology
- Pediatric Medicine
- Immunology
Background:
- Coeliac disease is an autoimmune disorder triggered by gluten ingestion.
- Potential and latent forms of coeliac disease are increasingly recognized.
- Giardiasis is a common intestinal parasitic infection.
Observation:
- A child presented with symptoms of both coeliac disease and giardiasis.
- The patient received treatment solely for giardiasis, without a gluten-free diet.
- Diarrhea symptoms resolved, and small intestinal morphology returned to normal post-treatment.
Findings:
- Resolution of giardiasis infection led to a clinical and morphological remission of coeliac disease.
- The patient transitioned from active to a latent form of coeliac disease.
- This indicates that parasitic infections can influence the presentation and activity of coeliac disease.
Implications:
- Highlights the potential role of infections in modulating coeliac disease activity.
- Suggests a paradigm shift in managing coeliac disease in the presence of concurrent infections.
- Emphasizes the importance of considering latent coeliac disease and its clinical implications.
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