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Further reduction in stroke after off-pump coronary artery bypass grafting: a 10-year experience
N Trehan1, M Mishra, O P Sharma
1Escorts Heart Institute and Research Centre, New Delhi, India.
Insights
Off-pump coronary artery bypass (OPCAB) significantly reduces stroke risk after heart surgery. This study found OPCAB resulted in a 0.14% stroke rate, much lower than conventional methods.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Medical Technology
Background:
- Perioperative stroke is a serious complication following coronary artery bypass grafting (CABG).
- Conventional CABG carries a 3% to 7% incidence of neurologic complications.
- This study investigates neurologic sequelae in patients undergoing off-pump CABG (OPCAB).
Purpose of the Study:
- To evaluate the incidence of neurologic sequelae in patients who underwent off-pump coronary artery bypass (OPCAB).
- To assess the effectiveness of OPCAB in reducing stroke rates compared to conventional CABG.
Main Methods:
- A 10-year retrospective study (January 1990 - September 2000) of 2,800 patients undergoing OPCAB.
- OPCAB was initially selective for high-risk patients and later performed electively in 60-65% of cases.
- Data collected included patient demographics, graft numbers, and neurologic complications.
Main Results:
- Neurologic complications (stroke/transient ischemic attack) occurred in 0.14% of OPCAB patients.
- Overall hospital mortality for OPCAB was 2.14%, with 0.07% mortality from neurologic complications.
- Predicted mortality for the group was 3.86%, significantly higher than observed (p < 0.001).
Conclusions:
- Off-pump coronary artery bypass (OPCAB) significantly reduces the risk of stroke after CABG.
- OPCAB is particularly beneficial for high-risk patient groups.
- Improved surgical techniques and monitoring contribute to reduced stroke rates in CABG procedures.
Background:
Perioperative stroke is a devastating complication after coronary artery bypass grafting (CABG). The reported incidence of neurologic complications after conventional CABG is 3% to 7%. With improved monitoring and surgical techniques, we have been able to achieve a drastic reduction in the stroke rate in our institution. This study evaluates the incidence of neurologic sequelae in patients who underwent off-pump CABG.
Methods:
Over a 10-year period from January 1990 to September 2000, off-pump coronary artery bypass (OPCAB) operation was performed on 2,800 patients of the 18,037 patients undergoing CABG during that time frame at the Escorts Heart Institute and Research Centre. Initially, OPCAB was performed selectively in the high-risk group of patients (atheromatous aorta, renal impairment, chronic obstructive pulmonary disease, octogenarians, etc). Lately we performed multivessel OPCABs electively in about 60% to 65% of the patients undergoing CABG. Results. Mean age of the patients was 58.0 +/- 9.91 years (range 27 to 85 years) and mean number of grafts was 2.9 per patient. Neurologic complications (stroke/transient ischemic attack) occurred in 0.14% of patients. Overall hospital mortality in OPCAB patients was 2.14%, whereas mortality from neurologic complications was 0.07%. Predicted mortality (National Society of Thoracic Surgeons Cardiac Surgery Database Risk Model for CABG) for the entire patient group was 3.86% (p < 0.001). Conclusions. Although current techniques of monitoring and surgical procedures have significantly reduced the risk of stroke from CABG, our data strongly support OPCAB as a technique to further reduce stroke after CABG, especially in the high-risk group of patients.