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Updated: Jul 27, 2026

Assessment of Cerebral Lateralization in Children using Functional Transcranial Doppler Ultrasound (fTCD)
Published on: September 27, 2010
Right hemisphere contribution to developmental language disorder: Neuroanatomical and behavioral evidence
E Plante1, C Boliek, N Mahendra
1Department of Speech and Hearing Sciences, The University of Arizona, Tucson 85721-0071, USA. eplante@u.arizona.edu
Unlabelled:
Developmental language disorder (DLD) is identified by virtue of the verbal deficits that define it. However, numerous studies have also documented nonverbal deficits in this population. This study attempts to explain the co-occurrence of both verbal and nonverbal deficits in this population from a brain-based perspective. Two samples of adults selected for DLD were compared with subjects without such a history on verbal and nonverbal skills in exploratory and confirmatory studies. Subjects also received MRI scans, which were used to determine the relation between left- and right-hemisphere regions hypothesized to relate to the behavioral skills tested. Results revealed replicable differences between groups on both verbal and nonverbal tasks. In addition, a significant association between performance on tests sensitive to facial affect and spatial rotation with the gray matter volume within the right supramarginal gyrus was found in both samples. These results support the hypothesis of a right hemisphere contribution to the profile of DLD.
Learning Outcomes:
As a result of this activity, the participant will be able to describe evidence in support of a role for the right hemisphere in DLD.
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