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Updated: Jul 15, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Exercise and heart failure
1National Heart and Lung Institute, Imperial College of Science, Technology, and Medicine, Royal Brompton Hospital, London, United Kingdom. a.coats@ic.ac.uk
Exercise training improves exercise capacity and may reduce mortality in chronic heart failure (CHF) patients. This approach addresses underlying pathophysiological changes, offering a safe and effective intervention for CHF management.
Area of Science:
- Cardiology
- Exercise Physiology
- Rehabilitation Medicine
Background:
- Chronic heart failure (CHF) significantly impairs exercise tolerance and quality of life.
- Despite optimal therapy, many CHF patients experience debilitating symptoms.
- Systemic pathophysiological changes are linked to exercise limitations in CHF.
Purpose of the Study:
- To discuss factors limiting exercise capacity in CHF.
- To review controlled clinical trials of exercise testing in CHF.
- To explore the role of exercise training in improving outcomes for CHF patients.
Main Methods:
- Review of recent investigations into exercise limitation in CHF.
- Analysis of controlled clinical trials evaluating exercise testing and training.
- Discussion of pathophysiological changes and their correction through exercise.
Main Results:
- Exercise training is safe for carefully selected stable CHF patients.
- Exercise training can correct peripheral pathophysiological changes.
- Improvements in exercise capacity, morbidity, and potentially mortality are associated with exercise training in CHF.
Conclusions:
- Exercise training offers a viable strategy to enhance functional capacity in CHF.
- Addressing pathophysiological factors through exercise training can improve CHF patient outcomes.
- Further research supports exercise training as a component of CHF management.
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