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Safety of three toothbrushes.
1The Procter & Gamble Company, Cincinnati, Ohio, USA. he.t@pg.com
American Journal of Dentistry
|September 27, 2001
Summary
This study found electric toothbrushes (Crest Spin Brush, Colgate ActiBrush) to be as safe and well-tolerated as a manual toothbrush (Oral B 40). Mild adverse events like gingivitis occurred, with electric options showing better tolerability.
Area of Science:
- Oral hygiene research
- Dental product safety evaluation
- Clinical trial methodology
Background:
- Assessing the safety and tolerability of oral hygiene devices is crucial for consumer product development.
- Electric toothbrushes offer potential benefits in plaque removal, necessitating safety comparisons with manual counterparts.
Purpose of the Study:
- To evaluate the oral soft tissue safety and tolerability of two electric toothbrushes (Crest Spin Brush, Colgate ActiBrush) against a manual toothbrush (Oral B 40).
Main Methods:
- A 4-week, single-center, randomized, examiner-blind parallel study involving 104 subjects.
- Subjects used assigned toothbrushes twice daily for 60 seconds.
- Oral soft tissue examinations and interviews were conducted at baseline, 3 days, and 4 weeks.
Main Results:
- 18% of subjects experienced mild adverse events, primarily localized gingivitis.
- The manual toothbrush (Oral B 40) group reported more adverse events than electric groups at 4 weeks.
- Crest Spin Brush and Colgate ActiBrush demonstrated similar and favorable tolerability profiles, outperforming the manual brush.
Conclusions:
- Daily use of electric toothbrushes is at least as safe as manual toothbrushes for oral soft tissues.
- Crest Spin Brush and Colgate ActiBrush are generally well-tolerated, suggesting superior safety and tolerability compared to the tested manual toothbrush.