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Occurrence of supernumerary nipples in children with kidney and urinary tract malformations

I Grotto1, K Browner-Elhanan, D Mimouni

  • 1Department of General Pediatrics and Emergency Medicine, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel.

Pediatric Dermatology
|September 29, 2001
PubMed

Insights

This study found no association between supernumerary nipples and kidney or urinary tract malformations in children. Therefore, routine imaging is not recommended for asymptomatic children with supernumerary nipples.

Area of Science:

  • Pediatric Urology
  • Dermatology
  • Medical Genetics

Background:

  • The relationship between congenital anomalies like supernumerary nipples and internal malformations, specifically of the kidney and urinary tract, remains unclear.
  • Previous studies have reported conflicting data regarding this association.

Purpose of the Study:

  • To investigate the association between supernumerary nipples and kidney and urinary tract malformations in a pediatric cohort.
  • To determine if radiographic or ultrasonographic evaluation is warranted in asymptomatic children with supernumerary nipples.

Main Methods:

  • A cohort of 200 children (ages 1 month-16 years) with recurrent urinary tract infections were assessed for supernumerary nipples.
  • Patients were stratified into groups based on the presence (n=92) or absence (n=108) of urinary tract malformations confirmed by radiographic studies.
  • All participants underwent thorough physical examination for supernumerary nipples, including assessment for abnormal pigmentation along the milk line and ectopic nipples.

Main Results:

  • Supernumerary nipples were identified in two children with confirmed urinary tract pathology and two children without urinary tract pathology.
  • The odds ratio for having supernumerary nipples in children with urinary tract malformations was 1.18 (95% CI: 0.084-16.53, p=0.627), indicating no statistically significant association.
  • No significant correlation was found between the presence of supernumerary nipples and kidney or urinary tract malformations.

Conclusions:

  • The study concludes that there is no significant association between supernumerary nipples and kidney or urinary tract malformations in children.
  • Routine radiographic or ultrasonographic investigation of the urinary tract is not recommended for asymptomatic children presenting with supernumerary nipples.
  • Clinical vigilance for other congenital anomalies should guide further investigations, not the presence of supernumerary nipples alone.

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