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LTP gets culture
1Programmes in Brain and Behaviour and Cell Biology, Hospital for Sick Children, Toronto, Canada. mike.salter@utoronto.ca
Trends in Neurosciences
|September 29, 2001
Abstract:
In a recent breakthrough, a methodology has been developed for studying persistent enhancement of excitatory synaptic transmission in primary cultures of hippocampus. Results from the use of this method have already pointed to a previously unsuspected differential role for synaptic versus extrasynaptic NMDA receptors in lasting synaptic potentiation.