Related Experiment Videos
[Autism and associated pathologies. Clinical study of 295 cases involving development disorders]
1Service Universitaire d'Explorations fonctionnelles et neurophysiologie en Pédopsychiatrie, CHRU de Tours, Service Universitaire de Pédopsychiatrie, Hôpital Bretonneau, F 37044 Tours.
Presse Medicale (Paris, France : 1983)
|October 2, 2001
Summary
Medical factors are common in children with major developmental disorders. This study highlights the need for multidisciplinary collaboration to improve diagnosis and management of these conditions.
Area of Science:
- Developmental disorders in children
- Autism spectrum disorder comorbidities
- Pediatric neurodevelopmental conditions
Context:
- Autism and associated disorders have been recognized since 1943.
- Previous studies report a wide range (10-37%) of associated diseases in autism.
- Understanding these comorbidities is crucial for both theoretical and practical aspects of care.
Purpose:
- To investigate the frequency of associated medical factors in children with major developmental disorders.
- To categorize these medical factors into hereditary diseases, serious medical conditions, minimal physical disorders, and perinatal antecedents.
- To analyze the co-occurrence of these factors and perinatal antecedents.
Summary:
- A retrospective review of 295 children with major developmental disorders (DSM IV criteria) was conducted.
- Results showed 26.5% had hereditary diseases, 19% serious medical conditions, and 21.7% minimal physical disorders.
- Ante- or perinatal antecedents were present in 34.4% of those with serious medical conditions and 77% of those without any medical factor.
Impact:
- The study underscores the significant prevalence of medical factors in major developmental disorders.
- It emphasizes the necessity of multidisciplinary collaboration among child psychiatrists, pediatricians, and geneticists.
- Identifying subgroups based on associated diseases may aid research into pathogenic mechanisms and personalized management.