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Related Experiment Videos

Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction.

S D Anderson1, G J Argyros, H Magnussen

  • 1Department of Respiratory Medicine, Level 9 Page Chest Pavilion, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia. sandya@mail.med.usyd.edu.au

British Journal of Sports Medicine
|October 2, 2001
PubMed
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The International Olympic Committee Medical Commission (IOC-MC) now requires athletes to provide evidence for beta(2) agonist use. Eucapnic voluntary hyperpnoea (EVH) is the recommended test to diagnose exercise-induced bronchoconstriction (EIB).

Area of Science:

  • Sports Medicine
  • Pulmonary Physiology
  • Anti-Doping Regulations

Background:

  • The International Olympic Committee Medical Commission (IOC-MC) mandates notification for beta(2) agonist use during the Winter Olympic Games.
  • This notification requires objective evidence justifying the need for medication seven days prior to the event.

Purpose of the Study:

  • To outline the IOC-MC's stance on beta(2) agonist use in elite athletes.
  • To present eucapnic voluntary hyperpnoea (EVH) as the optimal laboratory method for diagnosing exercise-induced bronchoconstriction (EIB).

Main Methods:

  • The study describes the eucapnic voluntary hyperpnoea (EVH) test, a specific challenge test designed to identify EIB.
  • The EVH test involves subjects hyperventilating dry air with 5% carbon dioxide for six minutes.

Related Experiment Videos

  • Ventilation is targeted at 30 times the subject's forced expiratory volume in one second (FEV(1)), with conditions adjustable to mimic athlete-specific triggers.
  • Main Results:

    • A positive test for EIB is defined as a 10% or greater reduction in FEV(1) compared to pre-test values.
    • EVH has a proven track record, having been successfully performed in thousands of subjects in both laboratory and field settings.

    Conclusions:

    • Eucapnic voluntary hyperpnoea (EVH) is currently considered the gold standard for confirming exercise-induced bronchoconstriction (EIB) in athletes.
    • The IOC-MC utilizes EVH results to validate the necessity of beta(2) agonist use in competitive sports.