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Outcomes after emergency department discharge with a primary diagnosis of heart failure
J E Rame1, M A Sheffield, D L Dries
1Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-9034, USA.
Insights
High rates of outpatient therapy failure occur in patients discharged from the emergency department with chronic heart failure (CHF). Increased respiratory rate upon arrival may predict adverse outcomes for these CHF patients.
Area of Science:
- Emergency Medicine
- Cardiology
- Public Health
Background:
- Patients with decompensated chronic heart failure (CHF) frequently visit emergency departments (EDs).
- Outcomes for CHF patients discharged from EDs to outpatient settings are poorly understood.
- Risk factors for readmission or repeat ED visits after CHF discharge are unknown.
Purpose of the Study:
- To investigate the outcomes of patients discharged from the ED with a primary diagnosis of CHF.
- To identify risk factors associated with failure of outpatient therapy within 3 months post-discharge.
Main Methods:
- A retrospective chart review of 112 patients discharged from an urban county hospital ED with CHF was conducted.
- A composite endpoint of recurrent ED visit, hospitalization for CHF, or death within 3 months was defined.
- Clinical and demographic variables were analyzed to identify predictors of the composite endpoint.
Main Results:
- 61% of patients experienced failure of outpatient therapy within 3 months.
- The median time to treatment failure was 30 days.
- Elevated respiratory rate at presentation was the sole independent predictor of adverse outcomes (OR 1.6 per 5 breaths/min increase).
Conclusions:
- A high failure rate (61%) exists for CHF patients discharged from EDs.
- Increased respiratory rate on ED presentation is a potential indicator of adverse outcomes in CHF patients post-discharge.
Background:
Patients with decompensated chronic heart failure (CHF) are frequently evaluated in emergency departments (ED). The outcomes of such patients after discharge to the outpatient setting from the ED are not well known. Risk factors for return ED visits or subsequent hospital admission after ED discharge for CHF also are not known.
Methods:
Charts were reviewed from all 112 patients discharged from the Parkland Memorial Hospital ED with a primary diagnosis of CHF from October to December 1998. A composite end point ("failure of outpatient therapy") was prespecified to be a recurrent ED visit for CHF, hospitalization for CHF, or death at 3 months after the index ED discharge.
Results:
Within 3 months of the index ED visit, 61% of the study population met the composite end point. The median time to failure of outpatient therapy was 30 days. Univariate analysis of 27 clinical and demographic variables demonstrated the respiratory rate at presentation as the only predictor of failure of outpatient therapy (P =.02). Multivariate analysis of a model with 8 prespecified variables also demonstrated respiratory rate to be the only variable independently associated with an increased risk for the composite end point (odds ratio 1.6, 95% confidence interval 1.1-2.6, for each increase of 5 breaths/min).
Conclusion:
There is a high rate of failure of outpatient therapy (61%) in patients discharged with a primary diagnosis of CHF from an urban county hospital ED. Increased respiratory rate on presentation to the ED may be associated with adverse outcomes after ED discharge for CHF.
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