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Updated: Aug 15, 2026
Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Reconstruction of posttraumatic long bone defect with free vascularized bone graft: good outcome in 48 patients with
1Orthopedic Department, Chang Gung Memorial Hospital, Taiwan. b491101@adm.cgmh.org.tw
Abstract:
We analyzed our clinical results in 48 patients (40 men) treated during 1990-1993 with free vascularized bone-graft reconstruction for bone defects, the follow-up being an average 6 (5-8) years. The bone defects were located in the femur (10), tibia (32), humerus (2), and forearm (4). We performed 41 fibula transfers, 4 iliac transfers, and 3 rib transfers in these patients. 3 patients required early revision surgery due to venous thrombosis. The average time needed for radiographic bone union was 4.2 months. Bone transfers to the lower extremity showed significantly more hypertrophy than those in the upper extremity. The functional outcome was good in 43 patients.
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