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Identification of two new HLA-B22 variants, HLA-B*5509 and B*5606
C E Voorter1, B G Hepkema, E M Mulkers
1Tissue Typing Laboratory, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands.
Tissue Antigens
|October 3, 2001
Abstract:
In our recent study using high-resolution HLA-B locus typing by sequence-based typing (SBT) we identified 9 new alleles in a total of 355 unrelated individuals (4). Three of them concerned an allele belonging to the B22 group. One of them, B*5607, showed the unusual presence of a Bw4 sequence motif, as described previously (5). In this report the other two B22 variants are described; one belonging to the B55 specificity and named B*5509; the other one being a B*56 allele and assigned B*5606, which brings the total number of alleles belonging to the B22 group to 18.