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Meningioma metastatic to thyroid gland
R Hasan1, M C Marshall, M Medhi
1Department of Medicine, Division of Endocrinology and Metabolism, New York Medical College and Westchester Medical Center, Valhalla, NY 10595.
Objective:
To describe the first reported case of meningioma metastasizing to and completely infiltrating the thyroid gland.
Methods:
We present a detailed case report, including radiographic, histologic, and immunostaining findings, in a patient with an atypical meningioma who had a progressively enlarging thyroid mass that proved to be a metastatic meningioma.
Results:
A 49-year-old man had a meningioma in the parieto-occipital region that had spread locally to the scalp and bone by the time of surgical resection. Local recurrence during the following year prompted repeated surgical resection, tumor embolization, radiotherapy, and chemotherapy. Despite aggressive therapy, the tumor progressed. A thyroid mass was first noted 2 years after the meningioma was diagnosed. Enlargement of the mass caused airway obstruction, necessitating an emergency thyroidectomy. Histologic examination of the thyroidectomy specimen showed that the thyroid gland had been extensively replaced by metastatic meningioma.
Conclusion:
To our knowledge, this is the first reported case of metastatic meningioma extensively infiltrating the thyroid gland. This case report expands the spectrum of tumors that metastasize to the thyroid gland.