[Morphological and histochemical changes in the spinal cord after epidural administration of prosidol in dogs]

Morphological, histochemical, and histoenzymatic changes in the nervous tissue of the spine and spinal ganglia after epidural injection of narcotic analgetic prosidol were studied in acute experiment on 12 mongrel dogs. No negative effect of prosidol on neuronal structure and nervous tissue microcirculatory bed were observed in experimental vs. control animals. The type of changes and their direction in various compartments of the nervous system (spine and spinal ganglia) were similar in control and experimental animals.