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Related Experiment Videos

Global efforts in structural genomics.

R C Stevens1, S Yokoyama, I A Wilson

  • 1Joint Center for Structural Genomics, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|October 6, 2001
PubMed
Summary
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A global structural genomics initiative is accelerating macromolecular structure determination through new investments and high-throughput technologies. An International Structural Genomics Organization has formed to guide policy and collaboration.

Area of Science:

  • Biochemistry
  • Genomics
  • Structural Biology

Background:

  • Genome projects have achieved significant success, paving the way for structural genomics.
  • There is substantial global investment in structural genomics research.
  • International collaboration is crucial for advancing the field.

Purpose of the Study:

  • To summarize the progress and organization of the worldwide structural genomics initiative.
  • To highlight advancements in high-throughput methodologies for structure determination.
  • To report the formation of the International Structural Genomics Organization.

Main Methods:

  • Leveraging successes from genome projects.
  • Investing in new high-throughput technologies.
  • Facilitating international meetings and collaborations.

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Main Results:

  • Enormous progress has been made in developing high-throughput methodologies.
  • Technologies to speed up macromolecular structure determination are advancing rapidly.
  • The International Structural Genomics Organization has been established.

Conclusions:

  • The structural genomics initiative is well-supported and progressing rapidly.
  • International cooperation is key to achieving the goals of structural genomics.
  • The field is poised to accelerate the determination of macromolecular structures.