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Related Experiment Videos

Density-dependent competition and selection on immune function in genetic lizard morphs.

E Svensson1, B Sinervo, T Comendant

  • 1Department of Ecology and Evolutionary Biology, Earth and Marine Sciences Building, University of California, Santa Cruz, CA 95064, USA. erik.svensson@zooekol.lu.se

Proceedings of the National Academy of Sciences of the United States of America
|October 11, 2001
PubMed
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Many territorial neighbors suppressed immune function in female lizards, impacting their fitness differently based on throat color. This led to a genetic correlation between female throat color and offspring immune response.

Area of Science:

  • Ecology
  • Evolutionary Biology
  • Animal Behavior

Background:

  • Density-dependent territorial interactions are hypothesized to cause immunosuppression and reduce fitness.
  • Empirical evidence from natural populations linking territoriality, immunity, and fitness is limited.

Purpose of the Study:

  • To investigate the relationship between territorial interactions, immune function, and fitness in a natural lizard population.
  • To examine how variation in immunological condition affects the fitness of different female morphs.
  • To determine if correlational selection has led to a genetic correlation between female morphotype and immune responsiveness.

Main Methods:

  • Field study of a natural population of Uta stansburiana (lizards).
  • Assessed breeding female immune function in relation to the number of territorial neighbors.

Related Experiment Videos

  • Analyzed the fitness consequences of immunological variation for different female morphs.
  • Quantified the genetic correlation between female throat color and offspring immune responsiveness.

    • Main Results:

    • Breeding female lizards with more territorial neighbors exhibited suppressed immune function.
    • Immunological condition differentially affected the fitness of two heritable female throat-color morphs.
    • Correlational selection occurred between female throat color and immune responsiveness.
    • A significant genetic correlation was found between a female's throat color and her daughter's immune responsiveness (r(A) = -1.36).

    Conclusions:

    • Density-dependent territoriality can suppress immune function and influence fitness in natural populations.
    • Interactions between immunity and heritable traits can drive correlational selection.
    • The study provides evidence for the buildup and preservation of genetic correlations between ecologically relevant traits (morphology and immunity).