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Published on: August 11, 2015
Treatment of ballism and pseudobulbar affect with sertraline
M S Okun1, A R Riestra, S E Nadeau
1Department of Neurology, Emory University, Atlanta, Ga, USA.
Background:
The pathogenesis of ballism is uncertain and may involve more than one mechanism; treatment is not always efficacious.
Objective:
To provide evidence of a nondopaminergic mechanism and the potential for a prompt and nearly complete response to a serotonergic agent.
Methods:
Report of 2 separate trials of sertraline hydrochloride in a single patient.
Results:
Complete remission of symptoms within 48 hours of each drug trial.
Conclusion:
Sertraline may offer an alternative with a better adverse effect profile than dopamine receptor blockers in the treatment of patients with ballism.
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