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Potent, low molecular weight thrombin receptor antagonists
S Chackalamannil1, D Doller, K Eagen
1Schering-Plough Research Institute, 2015 Galloping Hill Rd., Kenilworth, NJ 07033, USA. samuel.chackalamannil@spcorp.com
Bioorganic & Medicinal Chemistry Letters
|October 13, 2001
Abstract:
Several benzimidazole derivatives have been identified as potent thrombin receptor (PAR-1) antagonists as represented by compound 1h, which showed an IC(50) of 33 nM.
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