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Published on: April 21, 2014
Isolated non-compaction of ventricular myocardium: a report of three cases
1Department of Cardiology, Changi General Hospital, 2 Simei Street 3, Singapore 529889. khimleng@mailcityasia.com
Introduction:
Isolated non-compaction of ventricular myocardium (INVM) is a rare disorder of myocardial morphogenesis in the absence of other cardiac anomalies. Both sporadic and sex-linked recessive forms have been described. It can be identified with two-dimensional echocardiography.
Clinical Picture:
We report a series of 3 cases of adult males with INVM in June 2000. Clinical manifestations were congestive cardiac failure with severely depressed left ventricle systolic function and stroke. One patient had biventricular INVM.
Conclusion:
Early diagnosis of INVM is important as it is associated with a high incidence of cardiac failure, ventricular arrhythmia and remobilisation. Anticoagulation and screening of first-degree relatives is advisable.
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