Squamous cell carcinoma of both ears associated with hypercalcaemia

Area of Science:

• Oncology
• Otorhinolaryngology

Background:

• Squamous cell carcinoma (SCC) can present with aggressive local invasion.
• Understanding the systemic effects of advanced SCC is crucial for patient management.

Observation:

• A case of rapid, bilateral ear destruction by SCC is detailed.
• The patient exhibited transient biochemical abnormalities: hypercalcemia and hypophosphatemia.

Findings:

• Radiotherapy was administered to the affected areas.
• Post-treatment, the patient's biochemical profile normalized, resolving hypercalcemia and hypophosphatemia.

Implications:

• This case highlights the potential for SCC to cause rapid local destruction.
• The resolution of metabolic abnormalities post-radiotherapy suggests a link between tumor burden and these biochemical changes.
• Further research may elucidate the mechanisms behind SCC-associated metabolic disturbances and their response to treatment.