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Lithium use in octogenarians.

S Fahy1, B A Lawlor

  • 1Psychiatry of Old Age, Department of Psychiatry, St Camillus' Hospital, Shelbourne Road, Limerick, Ireland. sfahy@eircom.net

International Journal of Geriatric Psychiatry
|October 19, 2001
PubMed
Summary
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Lithium treatment is safe and well-tolerated in octogenarians, with specialized clinics ensuring optimal monitoring and management of potential side effects in elderly patients.

Area of Science:

  • Geriatric Psychiatry
  • Pharmacology

Background:

  • Lithium is a widely used mood stabilizer.
  • Its use in elderly populations requires careful consideration due to potential side effects.

Purpose of the Study:

  • To evaluate the tolerability and side-effect profile of lithium in octogenarians.
  • To assess the safety of long-term lithium treatment in this age group.

Main Methods:

  • Cross-sectional study of patients aged 80 and over attending a specialized lithium clinic.
  • Chart review to assess renal function, thyroid function, and side effects.

Main Results:

  • Twelve octogenarians (average age 83.6 years) on lithium for an average of 53.7 months were studied.
  • Mean serum lithium level was 0.42 mmol/l.

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  • No patient discontinued lithium due to side effects; transient renal abnormalities, one case of diabetes insipidus, and one case of hypothyroidism were noted.

    • Conclusions:

    • Lithium is well-tolerated and safely administered to octogenarians.
    • Specialized lithium clinics are recommended for monitoring serum levels and organ function in this population.