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The chemical revolution which arose between XVIIIth and XIXth centuries, had a special influence on the studies about living organisms and medicine. The idea was that the laboratory's discoveries could be applied to all the chemical transformation occurring in the human body. This point of view allowed the development of exerimental physiology and led to the birth of physiological chemistry; it influenced also a new theoretical discussion in medicine, by suggesting possible application to diagnostic and therapy. Paradoxically, in consideration of the importance of iatrochemistry in last centuries, the chemical revolution had a really small influence on medical systems.