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Updated: Oct 4, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Abstract:
Tholozan arrived in Persia in 1858 and remained there until his death in 1897. Personal physician of Nasreddin Shah with the title of hakim bachi, he was also appointed director of the Medical School of Teheran founded in 1850. He trained many Persian physicians and wrote medical treatises printed in persian. In 1866 he married in Teheran a widow of greco-italian origin from whom he had a daughter, Elise, who will have many descendants. Besides his important monographs on epidemic diseases (plague, cholera, etc.) Tholozan wrote in 1869 a "Rapport a S.M. le Shah sur l'etat de l'hygiene en Perse". He accompanied the Shah during his three voyages in Europe (1873, 1878, 1889) and stayed for his health three years in France after the last one, being replaced by Dr. Feuvrier as physician of the Shah. The friendly relations between Tholozan and the French archeologists Marcel and Jane Dieulafoy for whom he obtained from the Shah the permission to undertake diggings at Susa are recalled with the help of unpublished documents.
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