Giant cell lesion of the mandible in coincidental hyperparathyroidism and hyperthyroidism

A patient with hyperparathyroidism, thyrotoxicosis and a giant cell lesion of the mandible is reported. The hyperparathyroidism was secondary to renal hypoplasia and/or thyrotoxicosis. A review of the literature revealed other cases with giant cell lesions and secondary hyperparathyroidism. This study indicates that giant cell lesions are not specific for primary hyperparathyroidism.