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Related Experiment Videos

Heart transplantation 1958-1995.

N E Shumway

    Journal of the Irish Colleges of Physicians and Surgeons
    |January 1, 1995
    PubMed
    Summary

    Heart transplantation is a reality, but donor shortages persist, with only 10% of available donors utilized. New immunosuppressants worsen this critical organ scarcity, while xenografts and tolerance remain distant possibilities.

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    Area of Science:

    • Cardiovascular Surgery
    • Transplant Immunology
    • Organ Donation

    Background:

    • Heart transplantation has evolved from a century-old dream to a life-saving procedure for thousands annually.
    • A significant gap exists between the demand for donor hearts and the available supply, with only an estimated 10% of potential donors currently utilized.
    • Advancements in immunosuppressive therapies, while beneficial, inadvertently exacerbate the critical shortage of donor organs.