[Guido Vernoni and evolution of general pathology]

The new curriculum studiorum of medicine approved by Pope Leo XII in 1824, introduced the study of general pathology. A century later a new building was designated to this field when Guido Vernoni was nominated professor, following Amico Bignami, pupil of Marchiafava and working on malaria with a morphological approach. Vernoni shifted his attention on diseases as pathophysiological concatenation of events, evolving to the study of biochemical and molecular findings.