The concept of pain in the 17th century

The 17th century is very important in the history of sensation and pain. Philosophers, as Descartes, Hobbes, Spinoza, defined a new philosophy of science. Physicians of the iatro-chemical school introduced the first principles of biochemistry, tied to the sensations. Physicians of the iatro-mechanical school postulated a really modern concept: the importance of nerve juices in sensibility and pain.