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Updated: Oct 3, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and
1Laboratoire de Pharmacologie Cellulaire et Moléculaire, CNRS UMR 8612, Université de Paris Sud, Faculté de Pharmacie, Chatenay Malabry, France. haimtapiero@aol.com
Abstract:
Folate (folic acid, folacin) is an essential vitamin that is found in nature. Folates contain the core chemical structure of pteroylglutamic acid, but vary in their state of reduction, the single carbon moiety they bear and/or the length of the glutamate chain. At least 50% of whole body folate is stored in the liver. The influence of intracellular folate concentration depends largely on dietary intake. The supply of folate depends primarily on the quantity and bioavailability of ingested folate and the rate of loss by urinary and fecal routes and through catabolism.
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