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Progress in the Intercalation of Pyridine and Other Organic Bases into Crystalline Bismuth Molybdenum Oxide Hydrate,

N. Barnes1, S. J. Kitchin, J. A. Hriljac

  • 1School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.

Inorganic Chemistry
|October 24, 2001
PubMed
Abstract

No abstract available in PubMed .

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In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation02:47

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Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.

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