Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nascent ribosomes.

J R Warner1

  • 1Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. warner@aecom.yu.edu

Cell
|October 24, 2001
PubMed
Summary
This summary is machine-generated.

Ribosome biogenesis involves numerous RNA and protein factors. Recent studies reveal how these factors associate with intermediates during cytoplasmic ribosome synthesis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The monocistronic nature of ribosomal protein genes in yeast.

Current genetics·2013
Same author

Economics of ribosome biosynthesis.

Cold Spring Harbor symposia on quantitative biology·2003
Same author

N-hydroxyformamide peptidomimetics as TACE/matrix metalloprotease inhibitors: oral activity via P1' isobutyl substitution.

Bioorganic & medicinal chemistry letters·2001
Same author

Expression of a micro-protein.

The Journal of biological chemistry·2001
Same author

The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis.

Molecular and cellular biology·2001
Same author

The odyssey of a regulated transcript.

RNA (New York, N.Y.)·2001
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
Same journal

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Cell·2026
See all related articles

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Biochemistry

Background:

  • Ribosome biogenesis is a complex cellular process.
  • Hundreds of accessory factors are involved in converting ribosomal RNA transcripts into functional cytoplasmic ribosomes.

Purpose of the Study:

  • To investigate the association of processing factors with ribosome synthesis intermediates.
  • To provide insights into the early stages of cytoplasmic ribosome assembly.

Main Methods:

  • Observational studies analyzing factor association.
  • Biochemical analyses of ribosome biogenesis intermediates.

Main Results:

  • Identification of specific RNA and protein factors interacting with nascent ribosomes.

Related Experiment Videos

  • Characterization of the dynamic association of these factors during the synthesis pathway.

    • Conclusions:

    • These findings offer a first look at the intricate assembly process of cytoplasmic ribosomes.
    • Understanding factor association is crucial for comprehending ribosome biogenesis and cellular function.