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Simultaneous operations in thoraco-abdominal clinical oncology.
M I Davydov1, R S Akchurin, S S Gerasimov
1Surgical Department of Thoraco-Abdominal Oncology, N.N. Blokhin Memorial Cancer Research Centre of Russian Federation, Russian Academy of Medical Sciences, Kashirskoye sh. 24, 115478, Moscow, Russia.
Summary
Simultaneous operations for synchronous multiple primary malignant tumors (SMPTM) and severe heart disease improve cancer resectability. This approach offers promising outcomes for complex cancer patients, enhancing survival and quality of life.
Area of Science:
- Surgical Oncology
- Cardiovascular Surgery
- Thoracic Oncology
Background:
- Patients with synchronous multiple primary malignant tumors (SMPTM) and severe heart disease present complex treatment challenges.
- Traditional treatment approaches may limit options for radical tumor removal and cardiac intervention.
Purpose of the Study:
- To evaluate the efficacy of simultaneous operations in improving radical operability for SMPTM.
- To assess the outcomes of combined surgical procedures for thoracic/abdominal cancers and concomitant severe heart disease.
Main Methods:
- A retrospective analysis of 27 simultaneous operations performed for SMPMT (17 cases) and cancer with cardiac disease (10 cases).
- Procedures included lung cancer with gastric, esophageal, or laryngeal cancer, and coronary artery bypass grafting or valve surgery alongside lung resection or gastrectomy.
Main Results:
- Median survival for SMPMT patients was 26 months.
- Two early postoperative deaths occurred. One patient with cardiac disease and lung cancer died from cancer progression at 1 year.
- The remaining patients were followed up for 2 years with no evidence of cancer or heart disease.
Conclusions:
- Simultaneous operations enhance resectability, radicality, and functional operability in high-risk cancer patients.
- This surgical strategy holds promise for improving long-term outcomes in patients with complex comorbid conditions.