Chest pain. Differentiating GIT from cardiac causes
1Gastroenterology Unit, University of Sydney Concord Hospital, Concord, NSW 2139. pkatelar@mail.usyd.edu.au
Insights
Gastrointestinal issues frequently cause chest pain, mimicking cardiac problems. A thorough clinical history is crucial for diagnosing conditions like acid reflux and guiding appropriate treatment or investigations.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Chest pain is a common symptom in primary care, necessitating consideration of cardiac causes despite non-cardiac origins being more frequent.
- Gastrointestinal (GI) conditions, particularly esophageal disorders like reflux, hypersensitivity, and dysmotility, are common causes of non-cardiac chest pain.
Observation:
- This review focuses on identifying primary gastrointestinal origins of acute chest pain.
- Clinical history is paramount in differentiating causes and directing management strategies for chest pain.
Findings:
- Gastroesophageal reflux disease (GERD) is a frequent cause of chest pain, often responsive to high-dose antisecretory therapy.
- Diagnostic investigations such as endoscopy, ambulatory pH monitoring, barium swallow, and esophageal manometry are valuable when reflux is atypical or treatment-resistant.
Implications:
- Accurate diagnosis of GI-related chest pain improves patient outcomes and reduces unnecessary cardiac investigations.
- Understanding the spectrum of GI causes aids clinicians in selecting appropriate diagnostic pathways and therapeutic interventions for acute chest pain.
Background:
Chest pain is a common presenting symptom in general practice. Although a cardiac cause is not the commonest origin, a high index of suspicion is needed. When the diagnosis is not clear, a cardiac cause should be considered until proven otherwise. A gastrointestinal origin of chest pain is not infrequent and may be due to oesophageal, gastric or biliary disease. Oesophageal causes are most common and include reflux, hypersensitivity or dysmotility.
Objective:
This paper reviews the main gastrointestinal causes that may present with acute chest pain.
Discussion:
Clinical history taking is the key to decision making and guides the choice of prompt or routine investigation or a therapeutic trial. When reflux is suspected as the cause, a therapeutic trial of high dose antisecretory therapy is appropriate. Investigations may be helpful when typical reflux symptoms are not present or there is a poor response to this approach. Investigations may include endoscopy, ambulatory pH monitoring, barium swallow or oesophageal manometry.
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