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Pre-mRNA processing: insights from nonsense
1Brandeis University, Department of Biology, Waltham, Massachusetts 02454, USA. brogna@brandeis.edu
Current Biology : CB
|October 26, 2001
Abstract:
In eukaryotic cells, translation is thought to be confined to cytoplasm, but two recent studies have challenged this notion, one showing that an mRNA's open reading frame influences nuclear events as early as release from the site of transcription, and the other by providing evidence for protein synthesis within the nucleus.