Related Experiment Videos
Polyacetylene carboxylic acids from Mitrephora celebica
J R Zgoda1, A J Freyer, L B Killmer
1Graduate Program in Pharmacognosy, Department of Chemistry and Biochemistry, University of the Sciences in Philadelphia, 600 South 43rd Street, Philadelphia, PA 19104-4495, USA.
Journal of Natural Products
|October 27, 2001
Abstract:
A new polyacetylene carboxylic acid, 13(E),17-octadecadiene-9,11-diynoic acid (13,14-dihydrooropheic acid, 1), and the known 17-octadecene-9,11,13-triynoic acid (oropheic acid, 2) were isolated from the stem bark of Mitrephora celebica through bioassay-guided fractionation. Both compounds demonstrated significant activity against methicillin-resistant Staphylococcus aureus and Mycobacterium smegmatis.