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Evaluation of fluoride release from commercially available fluoride varnishes
J L Castillo1, P Milgrom, E Kharasch
1Department of Orthodontics, University of Washington, Seattle, USA.
Journal of the American Dental Association (1939)
|October 30, 2001
Summary
This study compared fluoride release from Duraphat and Duraflor varnishes in children's primary teeth. Duraphat showed higher fluoride release over a longer period, though both varnishes provided sustained fluoride availability.
Area of Science:
- Dental materials science
- Pediatric dentistry
- Caries prevention
Background:
- Limited fluoride release data exists for Duraphat and Duraflor varnishes.
- Clinicians need fluoride release information for caries-risk management in children.
Purpose of the Study:
- To evaluate and compare fluoride release from Duraphat and Duraflor varnishes.
- To provide clinicians with data on the fluoride release kinetics of these dental products.
Main Methods:
- Enamel slabs from primary molars were coated with Duraphat or Duraflor varnish.
- Samples were immersed in a simulated oral environment (buffered calcium phosphate solution) for six months.
- Fluoride release was measured weekly.
Main Results:
- Duraphat released significantly more fluoride than Duraflor from week 4 onwards.
- Duraphat released fluoride for 28 weeks, while Duraflor released it for 19 weeks.
- Fluoride release variability was greater with Duraflor than Duraphat.
Conclusions:
- Both Duraphat and Duraflor varnishes release fluoride for 5-6 months, supporting prolonged fluoride availability in plaque fluid.
- Differences in fluoride release kinetics exist between the two varnishes.
- Fluoride availability can vary between different tubes of the same product and between Duraphat and Duraflor.