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Updated: Aug 13, 2026

Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections
Published on: November 14, 2016
Cat scratch disease. A cause of regional lymphadenitis
1Nepean and Blue Mountains Hospitals, New South Wales. branlej@wahs.nsw.gov.au
Background:
In the last decade, the microbiological cause of cat scratch disease (CSD) has been determined using a combination of traditional culture and modern molecular techniques. A bacterium known as Bartonelia henselae is responsible for the vast majority of cases. The natural history of the disease is being reinterpreted in the light of more sophisticated diagnostic tools.
Objective:
To enable practitioners to have a sound basis for the diagnosis and treatment of cat scratch disease.
Discussion:
Bartonelia henselae is ubiquitous in the domestic feline and causes zoonotic infection in humans. Although this infection is usually self limiting and benign, it may cause more extensive disease in the immunosuppressed. Antibiotic therapy may hasten recovery.
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