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Role of muscular exercise in amyotrophic lateral sclerosis
M Sanjak1, W Reddan, B R Brooks
1Department of Neurology, University of Wisconsin Medical School, ALS Clinical Research Center, University of Wisconsin Hospital and Clinics, Madison 53792, USA.
Neurologic Clinics
|May 1, 1987
Abstract:
The general, systemic, and specific neuromuscular adaptation to physical exercise and training in healthy individuals is reviewed with application to individuals with neuromuscular disease in general and ALS in particular. A pilot study utilizing patients with ALS suggests the cardiopulmonary response to acute exercise is similar to normal individuals. However, a case study of a training response suggests the success of neuromuscular adaptation will be dependent upon the degree of motor neuron involvement.