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Ileoanal pouch function is related to postprandial pouch tone
J Steens1, W A Bemelman, W J Meijerink
1Department of Gastroenterology-Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
The British Journal of Surgery
|October 31, 2001
Summary
Patients with ileoanal pouches experience functional impairments. Postprandial pouch tone significantly increases in those with high stool frequency, impacting pouch function.
Area of Science:
- Gastroenterology
- Surgical outcomes
- Pouch function
Background:
- Functional impairments are common after ileoanal pouch surgery.
- Meal ingestion affects pouch tone and motility, but its influence on pouch function is not well understood.
Purpose of the Study:
- To investigate basal and postprandial pouch motor and sensory characteristics.
- To correlate these characteristics with clinical pouch function in ileoanal pouch patients.
Main Methods:
- Nineteen ileoanal pouch patients (8 high stool frequency, 11 adequate) underwent pouch distension with an electronic barostat.
- Pouch compliance and sensitivity were assessed, along with meal-stimulated pouch tone and motility.
Main Results:
- Pouch compliance and sensory characteristics (urge, pain) did not differ between groups.
- Postprandial pouch volume decreased significantly more in the high stool frequency group (70% vs 29%).
- Postprandial pouch contractions increased in both groups, with no difference between them.
Conclusions:
- Pouch compliance and sensitivity are similar in patients with normal and high stool frequency.
- Increased postprandial pouch tone is a significant finding in patients with high stool frequency after ileoanal pouch construction.