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Related Experiment Videos

Cranberries for preventing urinary tract infections.

R G Jepson1, L Mihaljevic, J Craig

  • 11F1, 130 Portobello High Street, Edinburgh, UK, EH15 1AH. ruthj@attglobal.net

The Cochrane Database of Systematic Reviews
|November 1, 2001
PubMed
Summary

Cranberry products show no reliable evidence for preventing urinary tract infections (UTIs). Poor trial quality and high dropout rates suggest limited effectiveness and acceptability for long-term UTI prevention.

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Area of Science:

  • Urology
  • Natural Products Research

Background:

  • Cranberries have a long history of use for preventing urinary tract infections (UTIs).
  • This review assesses the efficacy of cranberry products in UTI prevention.

Purpose of the Study:

  • To evaluate the effectiveness of cranberry juice and other cranberry products in preventing UTIs.
  • Focus on susceptible populations, including men, women, and children.

Main Methods:

  • Systematic review of randomized and quasi-randomized controlled trials.
  • Searched multiple databases and contacted manufacturers for relevant studies.
  • Narrative synthesis due to data heterogeneity; quality assessed using Cochrane criteria.

Main Results:

  • Five trials met inclusion criteria; four used cranberry juice, one used capsules.

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  • Limited evidence suggests potential effectiveness for symptomatic or asymptomatic UTIs in two trials.
  • Trials suffered from poor quality, small sample sizes, high dropout rates, and questionable reliability.

    • Conclusions:

    • No reliable evidence supports cranberry products for UTI prevention due to low-quality trials.
    • High dropout rates suggest poor long-term adherence to cranberry juice.
    • Further well-designed trials are necessary to establish conclusive evidence for UTI prevention.