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Matching reference materials with AOAC International methods of analysis
1US Department of Agriculture, Beltsville, MD, USA. wolf@bhnrc.usda.gov
Fresenius' Journal of Analytical Chemistry
|November 2, 2001
Summary
Ensuring equivalent analytical performance across labs requires validated methods and appropriate reference materials (RM). AOAC International is launching a peer-reviewed program to formally recognize specific RM matches for AOAC methods, enhancing reliability.
Area of Science:
- Analytical Chemistry
- Laboratory Science
- Method Validation
Background:
- Validated analytical methodology and appropriate reference materials (RM) are crucial for ensuring equivalent analytical performance in diverse laboratories.
- Selecting RMs that match the analyte, matrix, and method applicability is key for reliable results.
Purpose of the Study:
- To establish a formal program for recognizing the matching of specific reference materials (RM) to specific AOAC methods of analysis.
- To address requests for a standardized system for RM/method matching (RM/MM).
Main Methods:
- Implementation of a peer-reviewed selection system overseen by the AOAC Official Methods Board and the Technical Division on Reference Materials (TDRM) executive committee.
- Submission of potential RM/MM proposals to an RM/MM committee for technical review.
- Recommendation of acceptable matches for review through the existing AOAC process for new and modified methods.
Main Results:
- Development and testing of the RM/MM recognition system using several trial matches.
- Establishment of a structured process for validating RM suitability for specific AOAC methods.
Conclusions:
- The AOAC International Technical Division on Reference Materials (TDRM) is implementing a new program to formally recognize specific reference material (RM) and method matches.
- This initiative will enhance analytical method performance equivalence and provide a reliable resource for laboratories, available via document or online.