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Updated: Aug 2, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
[Second resection in patients with Ta-T1 bladder tumors]
F I Rodríguez-Rubio Cortadellas1, S Garrido Insua, D Rivas Aguayo
1Servicio de Urología, Hospital Universitario de Puerto Real, Cádiz.
A second transurethral resection (TUR) for superficial bladder tumors found residual or recurrent cancer in 37.8% of cases. This study suggests complete tumor removal is not always achieved after the initial TUR.
Area of Science:
- Urology
- Oncology
- Surgical Pathology
Context:
- Superficial bladder tumors require careful management to ensure complete eradication.
- Repeat transurethral resection (TUR) is sometimes performed to address potential residual or recurrent disease.
- The efficacy and necessity of a second TUR for Ta-T1 bladder tumors remain subjects of investigation.
Purpose:
- To determine the incidence of residual or recurrent bladder tumors after a second transurethral resection (2nd TUR).
- To evaluate the effectiveness of a second TUR in achieving complete tumor removal for superficial bladder cancer.
- To explore potential factors influencing tumor detection in a second TUR.
Summary:
- A repeat transurethral resection (TUR) was performed on 40 patients with superficial bladder tumors within three months of initial resection.
- Tumor was detected in 37.8% (14 of 37) of patients staged as Ta-T1 after the second TUR.
- No significant correlation was found between the presence of residual tumor and variables such as time between resections, tumor stage, grade, or size.
Impact:
- Findings indicate that complete tumor removal is not consistently achieved with initial transurethral resection (TUR) for superficial bladder tumors.
- The study highlights that early cystoscopy may miss residual disease.
- Routine second TUR for superficial bladder cancer is not recommended based on these findings, suggesting a need for refined surveillance strategies.
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