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Low-dose oral etidronate therapy for immobilization hypercalcaemia associated with Guillain-Barré syndrome
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1Department of Paediatrics, Otsu Red Cross Hospital, Japan. masumigo@mbox.kyoto-inet.or.jp
Acta Paediatrica (Oslo, Norway : 1992)
|November 8, 2001
Abstract
Unlabelled:
A low dose of oral etidronate (3.7 mg kg(-1) d(-1)) was administered for immobilization hypercalcaemia associated with Guillain-Barré syndrome in a 12-y-old boy. There was a slight increase in osteoblastic bone formation reflected by alkaline phosphatase and in particular bone-specific alkaline phosphatase during the treatment and serum calcium decreased to the normal range within 2 wk. No adverse side effects were observed and the patient's linear growth subsequently progressed.
Conclusion:
A low dose of oral etidronate is safe and effective for treatment of immobilization hypercalcaemia in children, without inhibiting bone formation.