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Extranodal cytotoxic T-cell lymphoma in a patient with X-linked agammaglobulinaemia
P Kanavaros1, D Rontogianni, D Hrissovergi
1Department of Histology, Medical Faculty, University of Thessalia, Hellas.
Leukemia & Lymphoma
|November 9, 2001
Abstract:
This report documents the occurrence of an extranodal cytotoxic peripheral T-cell lymphoma (PTCL) in a patient with X-linked agammaglobulinaemia (XLA). The diagnosis was based on the immunohistochemical detection of T-cell antigens and of the cytotoxic proteins TIA1 and Granzyme B in the tumour cells. This report provides further evidence that cytotoxic lymphomas are part of the differential diagnosis of neoplasia in patients with immunodeficiencies.