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Updated: Feb 14, 2026

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
Published on: June 20, 2025
CT signs and patterns of lung disease
1Department of Radiology, Graduate Medicine Education, University of Wisconsin Medical School and Hospital and Clinics, Madison 53792-3252, USA. jcollin4@facstaff.wisc.edu
Computed tomography (CT) findings can help diagnose lung diseases. Specific patterns like centrilobular nodules or tree-in-bud can suggest conditions such as hypersensitivity pneumonitis or small airway infections.
Area of Science:
- Radiology
- Pulmonary Medicine
- Diagnostic Imaging
Background:
- Computed tomography (CT) is crucial for evaluating lung abnormalities.
- Ground-glass patterns are common but nonspecific findings.
- Specific CT patterns can suggest particular diagnoses or disease processes.
Purpose of the Study:
- To review specific CT findings and their diagnostic implications in pulmonary diseases.
- To highlight how CT patterns can guide clinical diagnosis and management.
Main Methods:
- Review of characteristic CT patterns in various lung conditions.
- Correlation of imaging findings with clinical history and potential diagnoses.
- Discussion of differential diagnoses for common CT appearances.
Main Results:
- Centrilobular ground-glass nodules suggest hypersensitivity pneumonitis.
- Tree-in-bud pattern indicates small airway disease, often infectious.
- Honeycombing on HRCT confirms lung fibrosis.
- Specific signs like air bronchogram, air crescent, and split pleura have diagnostic value.
Conclusions:
- Specific CT patterns and signs are valuable for diagnosing pulmonary diseases.
- CT findings, when correlated with clinical context, can narrow differential diagnoses.
- CT imaging plays a vital role in identifying treatable lung conditions and guiding biopsies.
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