Related Experiment Video
Updated: Aug 12, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Keratitis caused by Candida glabrata in a patient with chronic granulomatous disease
A R Djalilian1, J A Smith, T J Walsh
1National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1863, USA. djalilia@inta.nei.nih.gov
Purpose:
To report an unusual ocular presentation of Candida glabrata in a patient with chronic granulomatous disease.
Methods:
Interventional case report. A 15-year-old boy with chronic granulomatous disease presented with bilateral limbal infiltrates. He had been receiving broad-spectrum systemic antibiotics for recurrent liver abscesses. The keratitis did not respond to antibiotics and did not resolve after a course of topical steroids.
Results:
Corneal cultures revealed Candida glabrata. The same species was simultaneously isolated from the surgical drainage of the liver abscesses. The ocular and hepatic findings resolved on intravenous amphotericin B.
Conclusion:
Candida glabrata has recently emerged as an important nosocomial pathogen. It may present as a limbal keratitis in the setting of systemic infection.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Glaucoma: Overview
Angle Closure Glaucoma: Treatment
Fungal Phylum Microsporidia
Cryptococcal Meningitis
Candidiasis

