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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
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Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

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Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

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Published on: February 2, 2017

The worldwide obesity epidemic.

P T James1, R Leach, E Kalamara

  • 1International Obesity task Force, London, United kingdom. jeanhjames@aol.com

Obesity Research
|November 15, 2001
PubMed
Summary
This summary is machine-generated.

The World Health Organization (WHO) standardized body mass index (BMI) classification enables global obesity analysis. Regional variations and factors like poverty and childhood stunting influence obesity prevalence worldwide.

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Area of Science:

  • Public Health
  • Epidemiology
  • Global Health

Background:

  • The World Health Organization (WHO) established a standardized body mass index (BMI) classification for global overweight and obesity analysis.
  • Asian populations show a demand for narrower normal BMI ranges (18.5–22.9 kg/m²) due to high comorbidity rates like diabetes and hypertension.
  • International Obesity Task-Force (IOTF) age-, sex-, and BMI-specific cutoff points are increasingly adopted for children.

Purpose of the Study:

  • To conduct a global analysis of body mass index (BMI) data as part of a new millennium assessment of the Global Burden of Disease.
  • To analyze data across 191 countries, considering over 20 principal risk factors contributing to major causes of disability and mortality.

Main Methods:

  • Utilizing standardized body mass index (BMI) data for comparable global prevalence analysis.
  • Evaluating BMI data globally for the Global Burden of Disease analysis.
  • Analyzing data within the World Health Organization (WHO) framework, considering multiple risk factors and country-specific prevalence.

Main Results:

  • Obesity prevalence rates vary significantly by region, with higher rates observed in the Middle East, Central and Eastern Europe, and North America.
  • Women generally exhibit higher BMI distribution and obesity rates compared to men across most countries.
  • Obesity is increasingly linked to poverty, even in developing nations, and abdominal obesity is associated with lower birth weight and childhood stunting.

Conclusions:

  • The standardized BMI classification facilitates global comparison of overweight and obesity prevalence.
  • Regional differences in BMI ranges and comorbidity profiles necessitate tailored public health approaches.
  • Future research should incorporate waist measurements in nationally representative studies to fully assess the global obesity epidemic's impact.