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Updated: Aug 17, 2026

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures
Published on: December 22, 2014
Rods are rods and cones cones, and (never) the twain shall meet
1Department of Ophthalmology, School of Medicine, F.M. Kirby Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
Abstract:
More than 100 photopigment G protein-coupled receptors (opsins) have been sequenced and organized into six classes. Rod photoreceptors in various species have been found to express an opsin from one of the two rhodopsin classes, while cones express an opsin from one of the four remaining classes. It has now been discovered that salamander short-wavelength sensitive cones and green rods express the same opsin, while manifesting other features that classically distinguish rods from cones.
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