Related Experiment Video
Updated: Jul 16, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Published on: October 15, 2013
Smart single-chip gas sensor microsystem
C Hagleitner1, A Hierlemann, D Lange
1Physical Electronics Laboratory, ETH Zurich, Switzerland.
Researchers developed a smart chemical microsensor system on a single chip. This innovative device integrates three sensor types for enhanced detection of volatile organic compounds, improving gas analysis capabilities.
Area of Science:
- Chemical sensing
- Materials science
- Microelectromechanical systems (MEMS)
Background:
- Current gas sensing research focuses on selective materials and sensor arrays for multi-component analysis.
- Integrated-circuit technology enables fabrication of planar and 3D microelectromechanical systems (MEMS) chemical sensors.
- Complementary metal-oxide silicon (CMOS) processes are used for metal oxide and acoustic-wave gas sensors.
Purpose of the Study:
- To fabricate a smart single-chip chemical microsensor system.
- To integrate multiple transduction platforms for enhanced chemical detection.
- To improve the performance and functionality of gas microsystems.
Main Methods:
- Combined complementary metal-oxide silicon (CMOS) processes with microelectromechanical systems (MEMS) fabrication.
- Integrated three different transducers (mass-sensitive, capacitive, calorimetric) on a single chip.
- Utilized sensitive polymeric layers for detecting airborne volatile organic compounds (VOCs).
Main Results:
- Successfully fabricated a smart single-chip chemical microsensor system.
- Achieved full integration of microelectronic and micromechanical components for sensor control and monitoring.
- Enabled on-chip signal amplification, conditioning, and analog-to-digital conversion for improved performance.
Conclusions:
- The developed single-chip system offers enhanced control, monitoring, and performance for chemical gas sensing.
- On-chip signal processing and data transmission capabilities were successfully implemented.
- This approach provides a foundation for future advancements in integrated gas microsensor systems.
More Related Videos
14:43Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
Published on: September 23, 2013
14:21Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope
Published on: July 24, 2021
Related Concept Videos
Gas Chromatography: Sample Injection Systems
Two primary injection methods are used...
Gas Chromatography: Overview of Detectors
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
Gas Chromatography: Types of Detectors-I
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
Gas Chromatography: Types of Detectors-II
iChip
Microbial Biosensors