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Synthesis and antimicrobial activity of new 3 alpha-hydroxy-23,24-bisnorcholane polyamine carbamates
1Department of Industrial Chemistry, Kyungpook National University, Taegu 702-701, South Korea. kimhs@knu.ac.kr
Bioorganic & Medicinal Chemistry Letters
|November 21, 2001
Abstract:
3 alpha-Hydroxy-23,24-bisnorcholane spermidine and spermine carbamates 2-7 have been synthesized and their antimicrobial and hemolytic activities were evaluated. They exhibited excellent in vitro activities especially against methicillin-resistant Staphylococcus aureus.